Bovine viral diarrhea virus (BVDV) infection is still a plague that causes important livestock pandemics. Despite the availability of vaccines against BVDV, and the implementation of massive eradication or control programs, this virus still constitutes a serious agronomic burden. Therefore, the alternative approach to combat Pestivirus...
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2018 (v1)PublicationUploaded on: April 14, 2023
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2008 (v1)Publication
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Uploaded on: March 27, 2023 -
2018 (v1)Publication
Two sets of benzimidazole derivatives were synthesised and tested in vitro for activity against promastigotes of Leishmania tropica and L. infantum. Most of the tested compounds resulted active against both Leishmania species, with IC50 values in the low micromolar/sub-micromolar range. Among the set of 2-(long chain)alkyl benzimidazoles, whose...
Uploaded on: April 14, 2023 -
2010 (v1)Publication
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Uploaded on: December 5, 2022 -
2013 (v1)Publication
Pyrimidopyrimidine derivatives 1 were prepared as rigid thioanalogues of merbarone (a catalytic topoisomerase II inhibitor) and screened as antiproliferative agents against different tumor cell lines. A number of the synthesized compounds emerged as cytotoxic in cell-based assays (MT-4, HeLa and MCF-7 cells) at low micromolar concentrations. In...
Uploaded on: April 14, 2023 -
2014 (v1)Publication
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Uploaded on: April 14, 2023 -
2008 (v1)Publication
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Uploaded on: December 5, 2022