The functional impairment of HIV-specific CD4(+) T cells during chronic HIV infection is thought to be closely linked to viral replication and to T cell exhaustion. T cell exhaustion in the presence of ongoing antigen exposure is a common feature of chronic viral infection, in which dysfunctional T cells fail to eliminate the virus. Otherwise,...
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2009 (v1)PublicationUploaded on: May 11, 2023
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2007 (v1)Publication
CTLA-4 molecule, expressed by activated T and B lymphocytes, transduces an inhibitory signal. Increasing evidence showed CTLA-4 gene as an important susceptibility locus for autoimmune endocrinopathies and other autoimmune disorders. The aim is to evaluate the augmented sCTLA-4 serum levels in different autoimmune thyroid diseases when compared...
Uploaded on: April 14, 2023 -
2010 (v1)Publication
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Uploaded on: March 31, 2023 -
2009 (v1)Publication
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Uploaded on: March 25, 2023