A. BACHI

Cyclic ADP-ribose (cADPR) is a second messenger modulating intracellular calcium levels. We have previously described a cADPR-dependent calcium signaling pathway in bovine rod outer segments (ROS), where calcium ions play a pivotal role. ROS ADP-ribosyl cyclase (ADPR-cyclase) was localized in the membrane fraction. In the present work, we...

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The present paper describes a new procedure for labelling living retinas, ex vivo, with fluorescent dyes, in order to image them by microscopy techniques by a procedure that maintains the physiological features of the tissue and its association with the retinal pigmented epithelium (RPE).

The vertebrate retina is an array of "narrowcapture" photoreceptive elements of diverse cellular types that allow the fine spatial resolution characteristic of vision. Imaging of photoreceptors and of the whole retina has been previously reported; however, both were achieved exclusively after fixation. We report our development of a new...

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