Objective: To evaluate the correlation of kinematic parameters of upper limb motor performance with brain dopaminergic function in Parkinson's disease (PD). Background: By means of 6-[18F]fluoro-l-dopa (FluoroDOPA) positron emission tomography (PET) both nigrostriatal and extra-nigrostriatal dopaminergic function can be imaged in PD. When...
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2012 (v1)PublicationUploaded on: March 31, 2023
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2012 (v1)Publication
Aim: Subtle cognitive impairment may be found in Parkinson's disease (PD) already at the time of diagnosis. The pathogenesis of this impairment is still matter of debate and could be heterogeneous, including changes in several neurotransmitter systems. The present study aims to unveil cognitive‐dopaminergic correlations in PD by assessing...
Uploaded on: April 14, 2023 -
2012 (v1)Publication
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Uploaded on: March 27, 2023 -
2012 (v1)Publication
Background Even at the early stage of Parkinson's Disease (PD) nuclear medicine‐ techniques, such as 123 I‐FP‐CIT SPECT and 123 I ‐MIBG scintigraphy, may reveal pathological findings, showing striatum and cardiac reduced uptake, respectively. This information about nigro‐striatal and sympathetic cardiac neuronal loss may contribute to the early...
Uploaded on: April 14, 2023