Adipocyte differentiation involves dramatic cell shape alterations that are accompanied by changes in the expression of cytoskeletal and extracellular matrix (ECM) proteins. Aortic carboxypeptidase-like protein (ACLP) is a secreted protein associated with the extracellular matrix whose expression is induced during smooth muscle (SM)...
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February 15, 2004 (v1)Journal articleUploaded on: December 4, 2022
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May 2003 (v1)Journal articleCharacterization of the long pentraxin PTX3 as a TNFalpha-induced secreted protein of adipose cells.
Exposure of preadipocytes to long-chain fatty acids induces the expression of several markers of adipocyte differentiation. In an attempt to identify novel genes and proteins that are regulated by fatty acids in preadipocytes, we performed a substractive hybridization screening and identified PTX3, a protein of the pentraxin family. PTX3 mRNA...
Uploaded on: December 4, 2022