A

A

ACHARYA , Abhinav

Last name: ACHARYA

First name: Abhinav

June 15, 2021 (v1)

Journal article

Metadata-only

Simultaneous Pharmacologic Inhibition of Yes‐Associated Protein 1 and Glutaminase 1 via Inhaled Poly(Lactic‐co‐Glycolic) Acid–Encapsulated Microparticles Improves Pulmonary Hypertension

Acharya, Abhinav Tang, Ying Bertero, Thomas

BACKGROUND: Pulmonary hypertension (PH) is a deadly disease characterized by vascular stiffness and altered cellular metabolism. Current treatments focus on vasodilation and not other root causes of pathogenesis. Previously, it was demonstrated that glutamine metabolism, as catalyzed by GLS1 (glutaminase 1) activity, is mechanoactivated by...

Uploaded on: December 4, 2022