ACOSTA LÓPEZ , Jorge

El tejido adiposo es el órgano de reserva energética más importante en los mamíferos y en la mayoría de las especies animales. Sus células pueden sintetizar y almacenar triglicéridos (TG), sustancia de alto valor calórico que ocupa poco volumen, hidrolizar estos TG y liberar ácidos grasos (AG). La velocidad con que ocurren ambos procesos en el...

In secretory cells, several exocytosis-coupled forms of endocytosis have been proposed including clathrin-mediated endocytosis, kiss-and-run endocytosis, cavicapture, and bulk endocytosis. These forms of endocytosis can be induced under different conditions, but their detailed molecular mechanisms and functions are largely unknown. We studied...

An endocytic vesicle is formed from a flat plasma membrane patch by a sequential process of invagination, bud formation and fission. The scission step requires the formation of a tubular membrane neck (the fission pore) that connects the endocytic vesicle with the plasma membrane. Progress in vesicle fission can be measured by the formation and...

Background/Aims: Microglia are the dynamic motile phagocytes of the brain considered the first line of defense against threats or disturbances to the Central Nervous System (CNS). Microglia help orchestrate the immunological response by interacting with others immune cells. Mast cells (MCs) are effector cells of the innate immune system...