2004 (v1)
Publication
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Uploaded on: March 31, 2023
A
Last name: AIELLO C.
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Background: Imatinib mesylate (STI-571, Gleevec) a small molecule tyrosine kinase inhibitor directed against the enzymatic domain of KIT protein, was recently found to produce dramatic clinical responses as monotherapy for metastatic GISTs. However, imatinib resistance can occur determining treatment failure. The present study was performed to...