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ALBUQUERQUE WENDT , Andreia

Last name: ALBUQUERQUE WENDT

First name: Andreia

April 20, 2022 (v1)

Publication

Metadata-only

Ros3 (Lem3p/CDC50) Gene Dosage Is Implicated in Miltefosine Susceptibility in Leishmania (Viannia) braziliensis Clinical Isolates and in Leishmania (Leishmania) major

Espada, Caroline R. Albuquerque Wendt, Andreia Hornillos, Valentín

The Ros3 protein is a component of the MT-Ros3 transporter complex, considered as the main route of miltefosine entry in Leishmania. L. braziliensis clinical isolates presenting differences in miltefosine susceptibility and uptake were previously shown to differentially express ros3. In this work, we showed that the ros3 gene copy number was...

Uploaded on: March 25, 2023