A

L

ALCARAZ , Lindsay

Last name: ALCARAZ

First name: Lindsay

2021 (v1)

Journal article

Metadata-only

A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment

Alcaraz, Lindsay Mallavialle, Aude David, Timothée

Rationale: Alternative therapeutic strategies based on tumor-specific molecular targets are urgently needed for triple-negative breast cancer (TNBC). The protease cathepsin D (cath-D) is a marker of poor prognosis in TNBC and a tumor-specific extracellular target for antibody-based therapy. The identification of cath-D substrates is crucial for...

Uploaded on: December 4, 2022