We present a simple mathematical model for simulating the movement of an actin cable that is attached to an external epithelial tissue, like in the case of the boundary of an epidermal wound. We focus on the case of non homogeneous forces for wound healing and for dorsal closure of drosophila.
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2012 (v1)Journal articleUploaded on: December 3, 2022
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November 18, 2010 (v1)Journal article
During embryogenesis, Drosophila embryos undergo epithelial folding and unfolding, which leads to a hole in the dorsal epidermis, transiently covered by an extraembryonic tissue called the amnioserosa. Dorsal Closure (DC) consists of the migration of lateral epidermis towards the midline, covering the amnioserosa. It has been extensively...
Uploaded on: December 3, 2022 -
August 17, 2018 (v1)Book section
The clinical question of drug resistance in cancer, our initial motivation to studycontinuous models of adaptive cell population dynamics, leads naturally and moregenerally to consider the cancer disease itself from an evolutionary biology view-point, a consideration without which even the best targeted therapies will likelymost often ...
Uploaded on: December 4, 2022