April 21, 2020 (v1)
Publication
PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks
Post-translational histone modifications and chromatin remodelling play a critical role controlling the integrity of the genome. Here, we identify histone lysine demethylase PHF2 as a novel regulator of the DNA damage response by regulating DNA damage-induced focus formation of 53BP1 and BRCA1, critical factors in the pathway choice for DNA...
Uploaded on: March 24, 2023