AMBROA , A.

Last name: AMBROA

First name: A.

August 28, 2020 (v1)

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Combined use of the Ab105-2фΔCI lytic mutant phage and different antibiotics in clinical isolates of multiresistant Acinetobacter baumannii

Blasco, L. Ambroa, A. López, M.

Phage therapy is an abandoned antimicrobial therapy that has been resumed in recent years. In this study, we mutated a lysogenic phage from Acinetobacter baumannii into a lytic phage (Ab105-2phiΔCI) showing antimicrobial activity against A.baumannii clinical strains(such as Ab177_GEIH-2000 which showed MICs to meropenem and ...

Uploaded on: March 25, 2023
October 6, 2020 (v1)

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Relationship Between the Quorum Network (Sensing/Quenching) and Clinical Features of Pneumonia and Bacteraemia Caused by A. baumannii

Fernandez-Garcia, Laura Ambroa, A. Blasco, L.

Acinetobacter baumannii (Ab) is one of the most important pathogens associated with nosocomial infections, especially pneumonia. Interest in the Quorum network, i.e., Quorum Sensing (QS)/Quorum Quenching (QQ), in this pathogen has grown in recent years. The Quorum network plays an important role in regulating diverse virulence factors such as...

Uploaded on: December 2, 2022
December 18, 2020 (v1)

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Mechanisms of Tolerance and Resistance to Chlorhexidine in Clinical Strains of Klebsiella pneumoniae Producers of Carbapenemase: Role of New Type II Toxin-Antitoxin System, PemIK

Bleriot, Inés Blasco, L. Delgado Valverde, María Mercedes

Although the failure of antibiotic treatment is normally attributed to resistance, tolerance and persistence display a significant role in the lack of response to antibiotics. Due to the fact that several nosocomial pathogens show a high level of tolerance and/or resistance to chlorhexidine, in this study we analyzed the molecular mechanisms...

Uploaded on: December 5, 2022

AMBROA , A.

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