No description
-
2023 (v1)PublicationUploaded on: February 11, 2024
-
2019 (v1)Publication
The main focus of cardio-oncology has been the prevention and treatment of the cardiac toxicity of chemotherapy and radiotherapy. Furthermore, several targeted therapies have been associated with unexpected cardiotoxic side-effects. Recently, epidemiological studies reported a higher incidence of cancer in patients with heart failure (HF)...
Uploaded on: April 14, 2023 -
2020 (v1)Publication
No description
Uploaded on: April 14, 2023 -
2018 (v1)Publication
No description
Uploaded on: April 14, 2023 -
2021 (v1)Publication
Non-vitamin K oral anticoagulants (NOACs) are the first choice for prophylaxis of cardioembolism in patients with non-valvular atrial fibrillation (AF) who are anticoagulant-naïve, as well as the preferable anticoagulation strategy in those who are on vitamin K antagonists (VKAs), but with a low time in therapeutic range (TTR). Nonetheless,...
Uploaded on: February 14, 2024 -
2023 (v1)Publication
AimsThis study aimed to determine whether any change occurred over time in level of evidence (LoE) of therapeutic interventions supporting heart failure (HF) and other European Society of Cardiology guideline recommendations. Methods and resultsWe selected topics with at least three documents released between 2008 and April 2022. Classes of...
Uploaded on: February 11, 2024 -
2018 (v1)Publication
The effects of intense glycaemic control on macrovascular complications in patients with type 2 diabetes are incompletely resolved, and many glucose-lowering medications negatively affect cardiovascular outcomes. Recently, the EMPA-REG OUTCOME trial revealed that empagliflozin, an inhibitor of the sodium-glucose cotransporter 2 (SGLT2),...
Uploaded on: April 14, 2023 -
2022 (v1)Publication
No description
Uploaded on: February 4, 2024 -
2017 (v1)Publication
The knowledge of the cellular events occurring in the aging heart has dramatically expanded in the last decade and is expected to further grow in years to come. It is now clear that impaired function and loss of cardiomyocytes are major features of cardiac aging, but other events are likewise important. In particular, accumulating experimental...
Uploaded on: April 14, 2023 -
2018 (v1)Publication
A variety of paracrine signals create networks within the myocardium and mediate intercellular communications. Indeed, paracrine stimulation of the endogenous regenerative program of the heart, mainly based on resident cardiac progenitor cell (CPC) activation together with cardiomyocyte proliferation, has become increasingly relevant for future...
Uploaded on: April 14, 2023 -
2023 (v1)Publication
Aims Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have been evaluated in phase 3 randomized- controlled trials (RCTs) that enrolled individuals with heart failure and preserved ejection fraction (HFpEF) based on detailed clinical, biochemical, and echocardiographic criteria (hereafter HF-RCTs), and in cardiovascular outcomes trials...
Uploaded on: February 13, 2024 -
2019 (v1)Publication
No description
Uploaded on: April 14, 2023