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AMIA , Rafika

Last name: AMIA

First name: Rafika

March 27, 2022 (v1)

Journal article

Metadata-only

Evolution of Bacterial Persistence to Antibiotics during a 50,000-Generation Experiment in an Antibiotic-Free Environment

Mathé-Hubert, Hugo Amia, Rafika Martin, Mikaël

Failure of antibiotic therapies causes > 700,000 deaths yearly and involves both bacterial resistance and persistence. Persistence results in the relapse of infections by producing a tiny fraction of pathogen survivors that stay dormant during antibiotic exposure. From an evolutionary perspective, persistence is either a 'bet-hedging strategy'...

Uploaded on: April 5, 2025