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AMROLLAHI-SHARIFABADI , Mohammad

Last name: AMROLLAHI-SHARIFABADI

First name: Mohammad

2020 (v1)

Publication

Metadata-only

Cardiomyocyte-Specific JunD Overexpression Increases Infarct Size following Ischemia/Reperfusion Cardiac Injury by Downregulating Sirt3

Akhmedov, Alexander Montecucco, Fabrizio Costantino, Sarah

Ischemia/reperfusion (I/R) injury in acute myocardial infarction activates several deleterious molecular mechanisms. The transcription factor JunD regulates pathways involved in oxidative stress as well as in cellular proliferation, differentiation, and death. The present study investigated the potential role of JunD as a modulator of...

Uploaded on: April 14, 2023
2021 (v1)

Publication

Metadata-only

TNFα induces endothelial dysfunction in rheumatoid arthritis via LOX-1 and arginase 2: reversal by monoclonal TNFα antibodies

Akhmedov, Alexander Crucet, Margot Simic, Branko

Aims: Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting joints and blood vessels. Despite low levels of low-density lipoprotein cholesterol (LDL-C), RA patients exhibit endothelial dysfunction and are at increased risk of death from cardiovascular (CV) complications, but the molecular mechanism of action is unknown.We aimed...

Uploaded on: April 14, 2023