ARNULFO G.

Focal epilepsy is a chronic condition characterized by hyper-activity and abnormal synchronization of a specific brain region. For pharmacoresistant patients, the surgical resection of the critical area is considered a valid clinical solution, therefore, an accurate localization is crucial to minimize neurological damage. In current clinical...

The objective and automatic detection of the sleep–wake cycle (SWC) stages is essential for the investigation of its physiology and dysfunction. Here, we propose a machine learning model for the classification of SWC stages based on the measurement of synchronization between neural oscillations of different frequencies. Publicly available...

Purpose: Focal epilepsy is a neurological disease that can be surgically treated by removing area of the brain generating the seizures. The stereotactic electroencephalography (SEEG) procedure allows patient brain activity to be recorded in order to localize the onset of seizures through the placement of intracranial electrodes. The planning...

Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects ≈6 million people worldwide. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) reduces motor disability and improves quality of life in patients with advanced PD who have severe levodopa-induced motor complications. Precise targeting of STN regions is...

Community structure, or "modularity," is a fundamentally important aspect in the organization of structural and functional brain networks, but their identification with community detection methods is confounded by noisy or missing connections. Although several methods have been used to account for missing data, the performance of these methods...

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Background and objective: Choosing the most appropriate denoising method to improve the quality of diagnostic images maximally is key in pre-processing of diffusion MRI images. Recent advancements in acquisition and reconstruction techniques have questioned traditional noise estimation methods favoring adaptive denoising frameworks,...