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AYALA , Guillermo

Last name: AYALA

First name: Guillermo

March 14, 2017 (v1)

Publication

Metadata-only

The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons

García Martínez, José Delgado Ramos, Lidia Ayala, Guillermo

We analyzed 80 different genomic experiments, and found a positive correlation between both RNA polymerase II transcription and mRNA degradation with growth rates in yeast. Thus, in spite of the marked variation in mRNA turnover, the total mRNA concentration remained approximately constant. Some genes, however, regulated their mRNA...

Uploaded on: March 27, 2023