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AYRAL , Erwan

Last name: AYRAL

First name: Erwan

July 2009 (v1)

Journal article

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Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.

Sevalle, Jean Ayral, Erwan Hernandez, Jean-François

Amyloid-beta (Abeta) peptides production is thought to be a key event in the neurodegenerative process ultimately leading to Alzheimer's disease (AD) pathology. A bulk of studies concur to propose that the C-terminal moiety of Abeta is released from its precursor beta-amyloid precursor protein by a high molecular weight enzymatic complex...

Uploaded on: December 3, 2022
November 20, 2007 (v1)

Conference paper

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Activités gamma-secrétase et présénilinase impliquées dans la maladie d'Alzheimer : mise au point de substrats fluorimétriques et d'inhibiteurs

Checlerc, Frédéric Sévalle, Jean Lisowski, Vincent

No description

Uploaded on: December 3, 2022
November 18, 2005 (v1)

Journal article

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JLK Inhibitors : Isocoumarin Compounds as Putative Probes to Selectively Target the gama-Secretase Pathway

Checler, Frédéric Alves da Costa, Cristine Ayral, Erwan

International audience

Uploaded on: February 28, 2023