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AZZI , Angelo

Last name: AZZI

First name: Angelo

2020 (v1)

Publication

Metadata-only

Reduction of senescence-associated beta-galactosidase activity by vitamin E in human fibroblasts depends on subjects' age and cell passage number

Ricciarelli, Roberta Azzi, Angelo Zingg, Jean-Marc

Cell senescence is due to the permanent cell cycle arrest that occurs as a result of the inherent limited replicative capacity toward the Hayflick limit (replicative senescence), or in response to various stressors (stress-induced premature senescence, SIPS). With the acquisition of the senescence-associated secretory phenotype (SASP), cells...

Uploaded on: March 27, 2023
2003 (v1)

Publication

Metadata-only

Alpha-tocopherol induces expression of connective tissue growth factor and antagonizes tumor necrosis factor-alpha-mediated downregulation in human smooth muscle cells

Villacorta, Luis Graça-Souza, Aurélio V Ricciarelli, Roberta

The effect of alpha-tocopherol treatment on gene expression in human aortic vascular smooth muscle cells was analyzed by gene expression arrays. The expression of the connective tissue growth factor (CTGF) gene was induced by alpha-tocopherol 1.8-fold in gene array experiments, and similar results were also obtained by RT-PCR (1.7-fold) and at...

Uploaded on: March 27, 2023