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BÉTOUS , Delphine

Last name: BÉTOUS

First name: Delphine

January 2015 (v1)

Journal article

Metadata-only

Human monocyte recognition of adenosine-based cyclic dinucleotides unveils the A2a Gαs protein-coupled receptor tonic inhibition of mitochondrially induced cell death

Tosolini, Marie Pont, Frédéric Bétous, Delphine

Cyclic dinucleotides are important messengers for bacteria and protozoa and are well-characterized immunity alarmins for infected mammalian cells through intracellular binding to STING receptors. We sought to investigate their unknown extracellular effects by adding cyclic dinucleotides to the culture medium of freshly isolated human blood...

Uploaded on: December 4, 2022