2011 (v1)
Publication
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Uploaded on: April 14, 2023
B
R
BORGHI , Roberta
Last name: BORGHI
First name: Roberta
Institution: UNIGE
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2011 (v1)Publication
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2013 (v1)Publication
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2014 (v1)Publication
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2012 (v1)Publication
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2004 (v1)Publication
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2003 (v1)Publication
Human embryonal carcinoma Ntera2/D1 (NT2) cells treated with retinoic acid (RA) differentiate into several cell types including post-mitotic neurons. In this study we asked if RA-induced differentiation alters the expression of RA and retinol (ROL) binding proteins. The regulation of the intracellular carrier proteins for ROL and RA, cellular...
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2007 (v1)Publication
We evaluated expression, protein levels and activity of the β-site cleaving enzyme (BACE1) as well as the amount of products of lipid peroxidation in frontal cortex of three groups of cases: sporadic Alzheimer's disease (AD); control subjects (CTR); cognitively normal subjects with abundant amyloid plaques (NA). We found a significant increase...
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2000 (v1)Publication
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2002 (v1)Publication
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2000 (v1)Publication
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2010 (v1)Publication
The search for markers that are able to predict the conversion of amnestic mild cognitive impairment (aMCI) to Alzheimer's disease (AD) is crucial for early mechanistic therapies. Using artificial neural networks (ANNs), 22 variables that are known risk factors of AD were analyzed in 80 patients with aMCI, for a period spanning at least 2...
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2005 (v1)Publication
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2004 (v1)Publication
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2013 (v1)Publication
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2005 (v1)Publication
Epidemiological and experimental data suggest that type 2 diabetes (DM2) and sporadic late-onset Alzheimer's disease (AD) share a common mechanism, that is able to produce accumulation of insulin and amyloid beta 42 (Abeta42), the major pathogenic events respectively of the two conditions. In 71 non diabetic patients with amnestic mild...
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2010 (v1)Publication
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2002 (v1)Publication
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2011 (v1)Publication
Alternative splicing generates protein isoforms that are conditionally or differentially expressed in specific tissues. Discovery of factors that control alternative splicing might clarify the molecular basis of biological and pathological processes. We found that IL1-α dependent upregulation of 38A, a small RNA polymerase III-transcribed...
Uploaded on: March 27, 2023