2013 (v1)
Publication
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Uploaded on: April 14, 2023
B
M
BOSCHETTI , Mara
Last name: BOSCHETTI
First name: Mara
Email: mara.boschetti@unige.it
Institution: UNIGE
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2013 (v1)Publication
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2005 (v1)Publication
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2011 (v1)Publication
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2010 (v1)Publication
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2013 (v1)Publication
The actions of somatostatin (SRIF) are mediated by specific G protein-coupled receptors, named SRIF receptor (SSTR) subtypes 1, 2, 3 and 5. SRIF binding to SSTR activates a series of second messenger systems, resulting in the inhibition of calcium channels and adenylate cyclase activity, ultimately leading to inhibition of hormone secretion,...
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2005 (v1)Publication
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2014 (v1)Publication
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2008 (v1)Publication
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2006 (v1)Publication
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2016 (v1)Publication
Gastroenteropancreatic (GEP) neuroendocrine tumors (NETs) are rare neoplasms with heterogeneous clinical behavior and potential long-term survival. In 2006/2007, the European Neuroendocrine Tumors Society introduced an important parameter, grade (based on mitoses and Ki-67 proliferation rate), which became part of the latest 2010-WHO...
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2012 (v1)Publication
The objective of this study is to assess the secretory pattern of GH after Oral Glucose Tolerance Test (OGTT) or day-curve (DC), in relation with IGF-I and to evaluate the influence of therapy on OGTT. A retrospective analysis in 279 OGTTs performed in 93 acromegalic patients in our unit from January 1988 to December 2005, in 77 patients also...
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2009 (v1)Publication
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2015 (v1)Publication
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2004 (v1)Publication
OBJECTIVE: It has been suggested that the threshold of 1 micro g/l of GH nadir after glucose load for definition of controlled acromegalic disease proposed in the 2000 consensus statement should be lowered to 0.30. We evaluated these two cut-off values in comparison with IGF-I, ALS and IGFBP-3 in a group of acromegalic patients. With the aim...
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2016 (v1)Publication
Background/Aim: The neuroendocrine tumor (NET) proliferation-based grading system (ENETS/WHO) for gastroenteropancreatic (GEP) tumors has proved reliable for prognostic stratification. To date, concerns exist regarding Ki-67 heterogeneity within the tumor and little is known on whether grade varies between primary and secondary sites. As tumor...
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2009 (v1)PublicationEffect of environment on growth: auxological and hormonal parameters in African and Italian children
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2015 (v1)Publication
OBJECTIVE: This prospective study aimed to evaluate the impact of growth hormone deficiency (GHD) on cardiac autonomic tone and on cardiovascular risk and the changes after 12 months of GH replacement therapy (GHRT). GHD is associated with increased cardiovascular morbidity and mortality. This has been attributed to increased markers of...
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2010 (v1)Publication
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