BRUZZI P.

Molecular epidemiology combines biological markers and epidemiological observations in the study of the environmental and genetic determinants of cancer and other diseases. The potential advantages associated with biomarkers are manifold and include: (a) increased sensitivity and specificity to carcinogenic exposures; (b) more precise...

ABSTRACT Background Adjuvant chemotherapy with anthracyclines improves disease-free and overall survival compared with non – anthracycline-based adjuvant chemotherapy regimens in the treatment of early breast cancer. The role of HER2 status as a marker of anthracycline responsiveness has been explored by subset analyses within randomized...

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Geographical variations - place of death - inappropriate hospital use - terminal phase - cancer disease