Salmonella enterica es una especie de bacteria patógena Gram negativa responsable de diversas enfermedades en animales como la gastroenteritis y la fiebre tifoidea. S. enterica expresa dos sistemas de secreción tipo III (T3SSs) relacionados con la virulencia codificados en las islas de patogenicidad de Salmonella 1 (SPI1) y SPI2,...
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November 11, 2016 (v1)PublicationUploaded on: December 4, 2022
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February 24, 2016 (v1)Publication
Salmonella enterica expresses two virulence-related type III secretion systems (T3SSs) encoded in Salmonella pathogenicity island 1 (SPI1) and SPI2, respectively. SseK1 is a poorly characterized substrate of the SPI2-encoded T3SS. Here, we show that this effector is essential to get full virulence both in oral and intraperitoneal mice...
Uploaded on: March 27, 2023 -
May 6, 2020 (v1)Publication
Salmonella enterica serovar Typhimurium is a human and animal pathogen that uses type III secretion system effectors to manipulate the host cell and fulfill infection. SseK1 is a Salmonella effector with glycosyltransferase activity. We carried out a yeast two-hybrid screen and have identified tubulin-binding cofactor B (TBCB) as a new binding...
Uploaded on: December 4, 2022