BALAS , Laurence

Branched fatty acid esters of hydroxy fatty acids are endogenous lipids reported to have antidiabetic and anti-inflammatory effects. Recently, we showed that 9-palmitic acid esters of hydroxypalmitic acid (9-PAHPA) and 9-oleic acid esters of hydroxypalmitic acid increased insulin sensitivity in mice when incorporated to a chow diet or to a high...

Alpha-linolenic acid (ALA), an essential omega-3 polyunsaturated fatty acid found in plants, exertsneuroprotection and anti-inflammatory effects in chronic and acute CNS disease models. However, theunderlying mechanisms are not yet understood. Since ALA is not incorporated into the brain, theobserved health benefits may result from some of its...

Obesity is a complex disease highly related to diet and lifestyle and is associated with low amount of thermogenic adipocytes. Therapeutics that regulate brown adipocyte recruitment and activity represent interesting strategies to fight overweight and associated comorbidities. Recent studies suggest a role for several fatty acids and their...

Whereas the anti-inflammatory properties and mechanisms of action of long chain. 3 PUFAs have been abundantly investigated, research gaps remain regarding the respective contribution and mechanisms of action of their oxygenated metabolites collectively known as oxylipins. A dose-dependent and comparative study was conducted using human primary...

The anti-inflammatory properties of omega 3 fatty acids have been largely demonstrated in vitro and in vivo but research gaps remain regarding the contribution of their oxygenated metabolites also called oxylipins. We aimed to investigate and compare the anti-inflammatory properties and potential mechanisms of action of different types of omega...

Whereas the anti-inflammatory properties and mechanisms of action of long chain. 3 PUFAs have been abundantly investigated, research gaps remain regarding the respective contribution and mechanisms of action of their oxygenated metabolites collectively known as oxylipins. A dose-dependent and comparative study was conducted using human primary...

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Whereas the anti-inflammatory properties and mechanisms of action of long chain. 3 PUFAs have been abundantly investigated, research gaps remain regarding the respective contribution and mechanisms of action of their oxygenated metabolites collectively known as oxylipins. A dose-dependent and comparative study was conducted using human primary...