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BALBI P.

Last name: BALBI P.

2011 (v1)

Publication

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Safe drugs to fight mutant protein overload and alpha-1-antitrypsin deficiency

Sechi G. Balbi P. Bachetti T.

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Uploaded on: April 14, 2023
2010 (v1)

Publication

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Correspondence regarding: Alexander disease mutant glial fibrillary acidic protein compromises glutamate transport in astrocytes J Neuropathol Exp Neurol 2010;69:335-45

Sechi G. Balbi P. Bachetti T.

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Uploaded on: April 14, 2023
2010 (v1)

Publication

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In vitro treatments with ceftriaxone promote elimination of mutant glial fibrillary acidic protein and transcription down-regulation

Bachetti T. Di Zanni E. Balbi P.

Alexander disease is a rare, untreatable and usually fatal neurodegenerative disorder caused by heterozygous mutations of the glial fibrillary acidic protein (GFAP) gene which ultimately lead to formation of aggregates, containing also ?B-Crystallin, HSP27, ubiquitin and proteasome components. Recent findings indicate that up-regulation of...

Uploaded on: April 14, 2023