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BALLEARI , Enrico

Last name: BALLEARI

First name: Enrico

2020 (v1)

Publication

Metadata-only

Iron overload alters the energy metabolism in patients with myelodysplastic syndromes: results from the multicenter FISM BIOFER study

Cilloni, Daniela Ravera, Silvia Calabrese, Chiara

Myelodysplastic syndromes (MDS) are hematological malignancies characterized by ineffective hematopoiesis and increased apoptosis in the bone marrow, which cause peripheral cytopenia. Mitochondria are key regulators of apoptosis and a site of iron accumulation that favors reactive oxygen species (ROS) production with detrimental effects on cell...

Uploaded on: April 14, 2023