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BALSEIRO-GÓMEZ , Santiago

Last name: BALSEIRO-GÓMEZ

First name: Santiago

October 11, 2022 (v1)

Publication

Metadata-only

The human-specific duplicated α7 gene inhibits the ancestral α7, negatively regulating nicotinic acetylcholine receptor-mediated transmitter release

Martín-Sánchez, Carolina Alés González de la Higuera, Eva María Balseiro-Gómez, Santiago

Gene duplication generates new functions and traits, enabling evolution. Human-specific duplicated genes in particular are primary sources of innovation during our evolution although they have very few known functions. Here we examine the brain function of one of these genes (CHRFAM7A) and its product (dupα7 subunit). This gene results from a...

Uploaded on: December 4, 2022