BANDINI , Giuseppe

Last name: BANDINI

First name: Giuseppe

2020 (v1)

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Transplantation Induces Profound Changes in the Transcriptional Asset of Hematopoietic Stem Cells: Identification of Specific Signatures Using Machine Learning Techniques

Cilloni, Daniela Petiti, Jessica Campia, Valentina

During the phase of proliferation needed for hematopoietic reconstitution following transplantation, hematopoietic stem/progenitor cells (HSPC) must express genes involved in stem cell self-renewal. We investigated the expression of genes relevant for self-renewal and expansion of HSPC (operationally defined as CD34+ cells) in steady state and...

Uploaded on: April 14, 2023
2009 (v1)

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Nonpermissive HLA-DPB1 disparity is a significant independent risk factor for mortality after unrelated hematopoietic stem cell transplantation

Crocchiolo, Roberto Zino, Elisabetta Vago, Luca

The importance of donor-recipient human leukocyte antigen (HLA)-DPB1 matching for the clinical outcome of unrelated hematopoietic stem cell transplantation (HSCT) is controversial. We have previously described an algorithm for nonpermissive HLA-DPB1 disparities involving HLA-DPB1*0901, *1001,*1701, *0301,*1401,*4501, based on T-cell...

Uploaded on: April 14, 2023
2016 (v1)

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Larger size of donor alloreactive NK cell repertoire correlates with better response to NK cell immunotherapy in elderly acute myeloid leukemia patients

Curti, Antonio Ruggeri, Loredana Parisi, Sarah

Purpose: In acute myeloid leukemia (AML), alloreactive natural killer (NK) cells are crucial mediators of immune responses after haploidentical stem cell transplantation. Allogeneic NK cell infusions have been adoptively transferred with promising clinical results. We aimed at determining whether the composition of NK graft in terms of...

Uploaded on: March 27, 2023

BANDINI , Giuseppe

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