B

K

BARNHAM , Kevin J.

Last name: BARNHAM

First name: Kevin J.

May 5, 2016 (v1)

Publication

Metadata-only

Intermolecular displacement of S-bound L-methionine on platinum(II) by guanosine 5′-monophosphate: Implications for the mechanism of action of anticancer drugs

Barnham, Kevin J. Djuran, Milos I. Murdoch, Piedad del Socorro

NMR investigations of the kinetics and thermodynamics of the competitive binding of L-methionine (Met), L-histidine (His), and 5′-monophosphates of guanosine (5′-GMP), adenosine (5′-AMP), thymidine (5′-TMP) and cytidine (5′-CMP) to [Pt(dien)Cl]+ (dien = 1,5-diamino-3-azapentane) in aqueous solution show that 5′-GMP selectively displaces S-bound...

Uploaded on: December 4, 2022