BELLOMO G.

After LHC is turned off, a new accelerator machine will be needed in order to explore unknown regions of high-energy particle physics. For this reason, the project Future Circular Collider (FCC) has started at CERN, with the target of studying the feasibility of a very large hadron collider with 50-TeV proton beams in a 100-km circumference....

SerpinA1 (α1-antitrypsin) is a soluble glycoprotein, the cerebrospinal fluid (CSF) isoforms of which showed disease-specific changes in neurodegenerative disorders that are still unexplored in Alz-heimer's disease (AD). By means of capillary isoelectric focusing immunoassay, we investigated six serpinA1 isoforms in CSF samples of controls (n =...

Introduction β-synuclein (β-syn) is a presynaptic protein, whose cerebrospinal fluid (CSF) levels are increased in patients with Alzheimer's diseases (AD) showing mild cognitive impairment (MCI) and dementia (dem). Here, we aimed to investigate CSF β-syn in subjects at different AD stages, including preclinical AD (pre-AD), and to compare its...