International audience
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September 8, 2017 (v1)Conference paperUploaded on: March 26, 2023
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2014 (v1)Journal article
BACKGROUND: This trial evaluated the feasibility and efficacy of combined sorafenib and irinotecan (NEXIRI) as second- or later-line treatment of patients with KRAS-mutated metastatic colorectal cancer (mCRC), who had progressed after irinotecan-based chemotherapy. METHODS: In Phase I, in a 3+3 dose escalation schedule, patients received...
Uploaded on: December 4, 2022 -
September 8, 2017 (v1)Conference paper
International audience
Uploaded on: February 28, 2023 -
April 2019 (v1)Journal article
PURPOSE:The role of chemotherapy has not been established in the treatment of metastatic squamous cell oesophageal cancer (mESCC).PATIENTS AND METHODS:E-DIS is a discontinuation trial, aimed at estimating efficacy, quality of life and safety of chemotherapy continuation (CT-CONT) in patients with mESCC who are free from progression after a...
Uploaded on: December 4, 2022