BENOIT , Evelyne

Natural substances have been of interest for several centuries and many toxins of animal, plant, bacterial or fungal origins have been identified and characterized. The evolution of technologies applied to biotoxinology has permitted considerable progress in the deciphering of their structure, of the molecular bases of their interaction with...

International audience

The French Society of Toxinology (SFET) organized its 27th annual meeting on 9–10 December 2021 as a virtual meeting (e-RT27). The central theme of this meeting was "Toxins: Mr Hyde or Dr Jekyll?", emphasizing the latest findings on plant, fungal, algal, animal and bacterial toxins during 10 lectures, 15 oral communications (shorter lectures)...

Huwentoxin-IV (HwTx-IV), a peptide discovered in the venom of the Chinese bird spider Cyriopagopus schmidti, has been reported to be a potent antinociceptive compound due to its action on the genetically validated NaV1.7 pain target. Using this peptide for antinociceptive applications in vivo suffers from one major drawback, namely its negative...