Super-enhancers (SEs) are stretches of enhancers ensuring a high level of expression of key genes associated with cell function. The identification of cancer-specific SE-driven genes is a powerful means for the development of innovative therapeutic strategies. Here, we identify a MITF/SOX10/TFIIH-dependent SE promoting the expression of BAHCC1...
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2023 (v1)Journal articleSuper-enhancer-driven expression of BAHCC1 promotes melanoma cell proliferation and genome stabilityUploaded on: January 19, 2024
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November 2023 (v1)Journal articleSuper-enhancer-driven expression of BAHCC1 promotes melanoma cell proliferation and genome stability
Super-enhancers (SEs) are stretches of enhancers ensuring a high level of expression of key genes associated with cell function. The identification of cancer-specific SE-driven genes is a powerful means for the development of innovative therapeutic strategies. Here, we identify a MITF/SOX10/TFIIH-dependent SE promoting the expression of BAHCC1...
Uploaded on: October 22, 2024