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July 2022 (v1)Journal articleUploaded on: December 3, 2022
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April 3, 2019 (v1)Journal article
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April 25, 2019 (v1)Journal article
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August 2018 (v1)Journal article
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2017 (v1)Book section
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December 8, 2020 (v1)Publication
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May 1, 2021 (v1)Journal article
Pulmonary arterial hypertension (PAH) refers to a set of heterogeneous vascular diseases defined by elevation of pulmonary arterial pressure (PAP) and pulmonary vascular resistance (PVR), leading to right ventricular (RV) remodeling and often death. Early increases in pulmonary artery stiffness in PAH drive pathogenic alterations of pulmonary...
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December 22, 2016 (v1)Journal article
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June 15, 2021 (v1)Journal article
BACKGROUND: Pulmonary hypertension (PH) is a deadly disease characterized by vascular stiffness and altered cellular metabolism. Current treatments focus on vasodilation and not other root causes of pathogenesis. Previously, it was demonstrated that glutamine metabolism, as catalyzed by GLS1 (glutaminase 1) activity, is mechanoactivated by...
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December 1, 2018 (v1)Journal article
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2009 (v1)Journal article
BACKGROUND: Epithelial-mesenchymal interactions are critical in regulating many aspects of vertebrate embryo development, and for the maintenance of homeostatic equilibrium in adult tissues. The interactions between epithelium and mesenchyme are believed to be mediated by paracrine signals such as cytokines and extracellular matrix components...
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September 2011 (v1)Journal article
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September 2011 (v1)Journal article
The mechanisms that regulate keratinocyte migration and proliferation in wound healing remain largely unraveled, notably regarding possible involvements of microRNAs (miRNAs). Here we disclose up-regulation of miR-483-3p in 2 distinct models of wound healing: scratch-injured cultures of human keratinocytes and wounded skin in mice. miR-483-3p...
Uploaded on: December 3, 2022