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BLANC , Ellen

Last name: BLANC

First name: Ellen

May 2018 (v1)

Journal article

Metadata-only

The tyrosine-kinase inhibitor sunitinib targets vascular endothelial (VE)-cadherin: a marker of response to antitumoural treatment in metastatic renal cell carcinoma

Polena, Helena Creuzet, Julie Dufies, Maeva

Vascular endothelial (VE)-cadherin is an endothelial cell-specific protein responsible for endothelium integrity. Its adhesive properties are regulated by post-translational processing, such as tyrosine phosphorylation at site Y685 in its cytoplasmic domain, and cleavage of its extracellular domain (sVE). In hormone-refractory metastatic breast...

Uploaded on: December 4, 2022