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BOCCIA , Daniele

Last name: BOCCIA

First name: Daniele

2022 (v1)

Publication

Metadata-only

Neurophysiological and behavioural correlates of ocrelizumab therapy on manual dexterity in patients with primary progressive multiple sclerosis

Dubbioso, Raffaele Bove, Marco Boccia, Daniele

Background Hand dexterity impairment is a key feature of disability in people with primary progressive multiple sclerosis (PPMS). So far, ocrelizumab, a recombinant humanized monoclonal antibody that selectively depletes CD20-expressing B cells, is the only therapy approved for PPMS and recent analysis reported its ability to reduce the risk of...

Uploaded on: February 14, 2024
2023 (v1)

Publication

Metadata-only

In-vivo characterization of macro- and microstructural injury of the subventricular zone in relapsing-remitting and progressive multiple sclerosis

Cellerino, Maria Schiavi, Simona Lapucci, Caterina

IntroductionThe subventricular zone (SVZ) represents one of the main adult brain neurogenesis niche. In-vivo imaging of SVZ is very challenging and little is known about MRI correlates of SVZ macro- and micro-structural injury in multiple sclerosis (MS) patients. MethodsThe aim of the present study is to evaluate differences in terms of volume...

Uploaded on: February 14, 2024