BOGDAN , Anamaria

Apathy and depression are two early behavioral symptoms in Alzheimer's disease and related disorders, that often occur before the onset of cognitive decline and memory disturbances. Both have been related to increased risk of conversion toward dementia.Objective: to assess both apathy and depression trajectories, using the Neuropsychiatric...

Apathy is one of the most frequent behavioral disturbances in many neurodegenerative disorders and is known to have a negative impact on the disease progression, particularly in Alzheimer's disease. Therapeutic options are currently limited and non-pharmacological approaches should constitute first line treatments. Pharmacological agents likely...

International audience

International audience

Background: Apathy and depression are two early behavioral symptoms in Alzheimer's disease (AD) and related disorders that often occur prior to the onset of cognitive decline and memory disturbances. Both have been associated with an increased risk of conversion to dementia, with a distinct neuropathology. Objective: The assessment of the...