BONCHE , Raphaël

The Basement Membrane (BM) is a specialised extracellular matrix which surrounds organs and provides them with a mechanical support. During development, the BM has to adapt to the morphogenesis of the tissues to which it is associated, i.e. to the changes of their volume and shape. This implies a modulation of the BM's biogenesis in terms of...

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All epithelia are surrounded by a specialized extracellular matrix, the basement membrane (BM). During development, this BM contributes to the morphogenesis of epithelial organs through different functions, the most recently added one being the shaping of the tissue. Seminal studies highlight the importance of the mechanical properties of the...