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BONFIGLIO , Ferdinando

Last name: BONFIGLIO

First name: Ferdinando

2022 (v1)

Publication

Metadata-only

Single-cell transcriptomics of neuroblastoma identifies chemoresistance-associated genes and pathways

Avitabile, Marianna Bonfiglio, Ferdinando Aievola, Vincenzo

High-Risk neuroblastoma (NB) survival rate is still <50%, despite treatments being more and more aggressive. The biggest hurdle liable to cancer therapy failure is the drug resistance by tumor cells that is likely due to the intra-tumor heterogeneity (ITH). To investigate the link between ITH and therapy resistance in NB, we performed a single...

Uploaded on: February 4, 2024
2021 (v1)

Publication

Metadata-only

Functional annotation and investigation of the 10q24.33 melanoma risk locus identifies a common variant that influences transcriptional regulation of OBFC1

Cardinale, Antonella Cantalupo, Sueva Lasorsa, Vito Alessandro

: The 10q24.33 locus is known to be associated with susceptibility to cutaneous malignant melanoma (CMM), but the mechanisms underlying this association have been not extensively investigated. We carried out an integrative genomic analysis of 10q24.33 using epigenomic annotations and in vitro reporter gene assays to identify regulatory...

Uploaded on: April 14, 2023