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BONINO B

Last name: BONINO B

2019 (v1)

Publication

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Uric acid and angiotensin II additively promote inflammation and oxidative stress in human proximal tubule cells by activation of toll-like receptor 4.

Milanesi S Verzola D Cappadona F

Renal proximal tubular cells (PTECs) participate in several mechanisms of innate immunity, express toll‐like receptors (TLRs), and proinflammatory cytokines. Hyperuricemia may be a promoter of inflammation and renal damage. Angiotensin II (Ang II) modulate immune and inflammatory responses in renal tubular cells. With the aim to evaluate the...

Uploaded on: April 14, 2023
2015 (v1)

Publication

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Trend of eGFR in an Italian cohort of mother-to-child HIV-infected patients exposed to tenofovir for at least 2 years.

GRIGNOLO, SARA TATARELLI, PAOLA GUSTINETTI, GIULIA

The aim of this study is to describe longitudinal changes in estimated glomerular filtration rate (eGFR) in a cohort of mother-to-child HIV-infected adolescents exposed to tenofovir dixoproxil fumarate (TDF) for at least 2 years. We retrospectively examined eGFR at starting TDF (T0), at 24 months (T2) and at the final assessment (T3)....

Uploaded on: December 5, 2022