BOYER , Julien

Contexte : Aucun critère diagnostique histologique positif de syndrome de l'intestin irritable n'existe. Objectif : 1/ Examiner la distribution des principales cellules inflammatoires de la muqueuse colique chez des sujets contrôles (SC) et des malades avec syndrome de l'intestin irritable (SII). 2/ Trouver des critères histologiques de...

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Highlights d AXL and c-MET are overexpressed in radiotherapy-and cisplatin-resistant HNSCC d Overexpression of AXL and c-MET contributes to tumor aggressiveness and poor prognosis d Cabozantinib has anti-tumor and anti-metastatic efficacy in mice and zebrafish models d Cabozantinib efficacy is shown on HNSCC biopsies and in one patient after...

Macrophages from human and mouse skin share phenotypic and functional features, but remain to be characterized in pathological skin conditions. Skinresident macrophages are known to derive from embryonic precursors or from adult hematopoiesis. In this report, we investigated the origins, phenotypes and functions of macrophage subsets in mouse...