B

BRAZDA V.

Last name: BRAZDA V.

2021 (v1)

Publication

Metadata-only

Evaluating the influence of a g-quadruplex prone sequence on the transactivation potential by wild-type and/or mutant p53 family proteins through a yeast-based functional assay

Monti P. Brazda V. Bohalova N.

P53, P63, and P73 proteins belong to the P53 family of transcription factors, sharing a common gene organization that, from the P1 and P2 promoters, produces two groups of mRNAs encoding proteins with different N-terminal regions; moreover, alternative splicing events at Cterminus further contribute to the generation of multiple isoforms. P53...

Uploaded on: April 14, 2023