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BROCHÉRIOU , Isabelle

Last name: BROCHÉRIOU

First name: Isabelle

December 2006 (v1)

Journal article

Metadata-only

Atherogenic properties of LDL particles modified by human group X secreted phospholipase A2 on human endothelial cell function.

Karabina, Sonia-Athina Brochériou, Isabelle Le Naour, Gilles

Increasing evidence suggests that secreted phospholipases A2 (sPLA2s) play an important role in the pathophysiology of atherosclerosis. Among sPLA2s, the human group X (hGX) enzyme has the highest catalytic activity toward phosphatidylcholine, one of the major phospholipid species of cell membranes and low-density lipoprotein (LDL). Our study...

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