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BRUNET , Joan

Last name: BRUNET

First name: Joan

2021 (v1)

Publication

Metadata-only

Altered regulation of BRCA1 exon 11 splicing is associated with breast cancer risk in carriers of BRCA1 pathogenic variants

Ruiz de Garibay, Gorka Fernandez-Garcia, Ignacio Mazoyer, Sylvie

Germline pathogenic variants in BRCA1 confer a high risk of developing breast and ovarian cancer. The BRCA1 exon 11 (formally exon 10) is one of the largest exons and codes for the nuclear localization signals of the corresponding gene product. This exon can be partially or entirely skipped during pre-mRNA splicing, leading to three major...

Uploaded on: February 6, 2024
2022 (v1)

Publication

Metadata-only

Immune checkpoint inhibitor therapy and outcomes from SARS-CoV-2 infection in patients with cancer: a joint analysis of OnCovid and ESMO-CoCARE registries

Cortellini, Alessio Dettorre, Gino M Dafni, Urania

Background: As management and prevention strategies against COVID-19 evolve, it is still uncertain whether prior exposure to immune checkpoint inhibitors (ICIs) affects COVID-19 severity in patients with cancer. Methods: In a joint analysis of ICI recipients from OnCovid (NCT04393974) and European Society for Medical Oncology (ESMO) CoCARE...

Uploaded on: February 14, 2024