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BRUNO O.

Last name: BRUNO O.

2023 (v1)

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Erratum: Correction: Biological evaluation of pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma (Oncotarget)

Marengo B. Meta E. Brullo C.

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Uploaded on: February 4, 2024
2020 (v1)

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Biological evaluation of pyrazolyl-urea and dihydro-imidazopyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma

Marengo B. Meta E. Brullo C.

Pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea compounds (STIRUR 13, STIRUR 41 and BUR 12) have been demonstrated to exert a strong inhibitory effect on interleukin 8 or N-formyl-methionyl-leucyl-phenylalanine-induced chemotaxis of human neutrophils. Since the migration of cancer cells is comparable to that of neutrophils, the purpose of...

Uploaded on: April 14, 2023
2021 (v1)

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New series of pyrazoles and imidazo‐pyrazoles targeting different cancer and inflammation pathways

Signorello M. G. Rapetti F. Meta E.

(1) Background: different previously synthesized pyrazoles and imidazo-pyrazoles showed interesting anti-angiogenic action, being able to interfere with ERK1/2, AKT and p38MAPK phosphorylation in different manners and with different potency; (2) Methods: here, a new small compound library, endowed with the same differently decorated chemical...

Uploaded on: April 14, 2023