CÓNDOR , M.

Traction force microscopy is a methodology that enables to estimate cellular forces from the measurement of the displacement field of an extracellular matrix (ECM)-mimicking hydrogel that a cell is mechanically interacting with. In this paper, a new inverse and physically-consistent methodology is developed and implemented in the context of 3D...

Traction force microscopy (TFM) allows to estimate tractions on the surface of cells when they mechanically interact with hydrogel substrates that mimic the extracellular matrix (ECM). The field of mechanobiology has a strong interest in using TFM in 3D in vitro models. However, there are a number of challenges that hamper the accuracy of 3D...