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1997 (v1)PublicationUploaded on: March 31, 2023
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1989 (v1)Publication
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1999 (v1)Publication
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Uploaded on: December 5, 2022 -
2011 (v1)Publication
The two major functions of human natural killer (NK) cells are conventionally associated with distinct cell subsets. Thus, cytolytic activity is mostly confined to the CD56(dim)CD16(+) subset, whereas cytokine production is generally assigned to CD56(bright)CD16(+/-) cells. In this study, we reevaluated the functional capabilities of these NK...
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1997 (v1)Publication
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Uploaded on: March 31, 2023 -
1999 (v1)Publication
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Uploaded on: April 14, 2023 -
1996 (v1)Publication
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Uploaded on: March 27, 2023 -
2014 (v1)Publication
The ability of tumors to manage an immune‐mediated attack has been recently included in the "next generation" of cancer hallmarks. In solid tumors, the microenvironment that is generated during the first steps of tumor development has a pivotal role in immune regulation. An intricate net of cross‐interactions occurring between tumor components,...
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2001 (v1)Publication
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Uploaded on: April 14, 2023 -
1999 (v1)Publication
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Uploaded on: April 14, 2023 -
2001 (v1)Publication
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Uploaded on: March 27, 2023 -
2003 (v1)Publication
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2003 (v1)Publication
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1994 (v1)Publication
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2017 (v1)Publication
Previous studies suggested that the cross talk between NK cells and other cell types is crucial for the regulation of both innate and adaptive immune responses. In the present study, we analyzed the phenotypic and functional outcome of the interaction between resting or cytokine-activated NK cells and eosinophils derived from non-atopic...
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2002 (v1)Publication
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Uploaded on: April 14, 2023 -
2008 (v1)Publication
During the first trimester of pregnancy NK cells represent >50% of the lymphoid cells present in the human decidua where they reside in close contact with trophoblast cells. Because in decidual tissues NK cell activation and function may be induced by this interaction, we analyzed the cellular ligands recognized by activating NK receptors...
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2017 (v1)Publication
Previous studies suggested that the cross talk between NK cells and other cell types is crucial for the regulation of both innate and adaptive immune responses1,2. In the present study, we analyzed the phenotypic and functional outcome of the interaction between resting or cytokine-activated NK cells and eosinophils derived from non-atopic...
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1992 (v1)Publication
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Uploaded on: March 27, 2023 -
2012 (v1)Publication
IL-18 is a proinflammatory cytokine belonging to the "IL-1 family" that has been shown to play a prominent role in the induction of type 1 immune responses. Here, we show that M-CSFinduces the expression of a membrane-bound form of IL-18 (mIL-18) in a subset of human blood monocytes differentiating toward macrophages. While monocytes, DC, and...
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2010 (v1)Publication
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Uploaded on: March 31, 2023 -
2009 (v1)Publication
C-C chemokine receptor type 7 (CCR7) is a chemokine receptor playing a pivotal role in the induction of human natural killer (NK)-cell migration to lymph nodes. We show that "licensed" peripheral blood killer immunoglobulin-like receptor-positive (KIR(+)) NK-cell populations, as well as KIR(+) NK-cell clones, de novo express CCR7 upon coculture...
Uploaded on: March 27, 2023