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1999 (v1)PublicationUploaded on: April 14, 2023
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2010 (v1)Publication
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Uploaded on: April 14, 2023 -
2010 (v1)Publication
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2009 (v1)Publication
PURPOSE. The anterior chamber of the eye is a highly specialized structure delimited by the cornea, lens, and iris. It contains the aqueous humor, secreted by the ciliary body and drained by the trabecular meshwork. Alteration of aqueous humor homeostasis plays a major role in the pathogenesis of glaucoma. The trabecular meshwork is the target...
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2003 (v1)Publication
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2001 (v1)Publication
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2011 (v1)Publication
Open-angle glaucoma appears to be induced by the malfunction of the trabecular meshwork cells due to injury induced by oxidative damage and mitochondrial impairment. Here, we report that, in fact, we have detected mitochondrial damage only in primary open-angle glaucoma and pseudo-exfoliation glaucoma, among several glaucoma types...
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2012 (v1)Publication
MicroRNAs (miRNAs) have been implicated in many biological processes, cancer, and other diseases. In addition, miRNAs are dysregulated following exposure to toxic and genotoxic agents. Here we review studies evaluating modulation of miRNAs by dietary and pharmacological agents, which could potentially be exploited for inhibition of mutagenesis...
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2003 (v1)Publication
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1997 (v1)Publication
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2011 (v1)Publication
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2004 (v1)Publication
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1999 (v1)Publication
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Uploaded on: December 5, 2022 -
2001 (v1)Publication
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2011 (v1)Publication
In the field of prevention, Internet websites and their related instruments constitute valuable tools for healthcare facilities, and particularly for Local Healthcare Authorities (LHA). As yet, however, their undoubted potential remains largely unexploited. Many LHA websites currently operating in Italy are organized in such a way that they...
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2010 (v1)Publication
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2002 (v1)Publication
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2013 (v1)Publication
Biphosphonate (BPN) are widely used in clinics to treat metastatic cancer and osteoporosis thus representing a problem not only for patients but also for workers involved in their preparation and administration. A similar exposure occurred years ago in match-making workers undergoing bone alterations similar to those consequent to BPN exposure....
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1999 (v1)Publication
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Uploaded on: December 5, 2022 -
1998 (v1)Publication
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2003 (v1)Publication
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2004 (v1)Publication
We previously showed that sunlight-mimicking light induces genotoxic damage not only in skin but also even in lung, bone marrow, and peripheral blood of hairless mice. Moreover, light and smoke acted synergically in the respiratory tract. To clarify the mechanisms involved, we investigated by cDNA-arrays the expression of 746 toxicologically...
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2003 (v1)Publication
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Uploaded on: April 14, 2023 -
2012 (v1)Publication
Dysregulation of microRNAs (miRNAs) has important consequences on gene and protein expression since a single miRNA targets a number of genes simultaneously. This article provides a review of published data and ongoing studies regarding the effects of cigarette smoke (CS), either mainstream (MCS) or environmental (ECS), on the expression of...
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2004 (v1)Publication
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Uploaded on: March 31, 2023